Topical Formulation & Drug Product Development

A great active is only as good as the formulation that delivers it. Neoventech develops topical, transdermal, and OTC drug products alongside their delivery systems, taking your program from concept to stable product and quickening the process with our combined formulation and testing functions.

Variety of Dosage Forms

We design and optimize formulations across the full range of topical and transdermal dosage forms, balancing stability, manufacturability, and delivery performance for your needs in sun care, antiacne, antiaging, pain control, and intimate care.

Dosage forms: cream · ointment · lotion · gel · emulsion (W/O & O/W) · foam · aerosol · shampoo · transdermal patch · dissolvable film · powder

Our formulation work covers: 

• Active and excipient selection, compatibility, and order-of-addition design 
• Emulsion architecture (water-in-oil and oil-in-water) for targeted deposition vs. systemic delivery 
• Penetration enhancement and skin-targeting strategies 
• Preservative systems, rheology, and sensory optimization 
• Prototype development through stability-confirmed formulation

Proprietary Drug Delivery Technology

Neoventech’s formulation edge is built on patented delivery science. Beyond the chemical compound in the jar, we pay attention and care to where and how an active ingredient is delivered. Some of our technologies include: 

• Film-forming & multi-layer topical systems — patented architectures for controlled, site-specific delivery
• Polymer-based controlled delivery — patented systems for enhancing topical application and modulating release of benefit agents
• Microstructure-engineered topicals — controlling the Q3 arrangement of matter to tune performance

Our delivery platforms, listed below, are backed by 50+ granted patents — learn more about our leadership.

505(b)(2) & Generic Topical Development

For companies pursuing generic or 505(b)(2) topical products, Neoventech can lay out the path from modeling the reference product to demonstrating equivalence.

• Deformulation of the reference listed drug to establish Q1 (qualitative) and Q2 (quantitative) sameness
• Q3 microstructure matching — particle/droplet size, rheology, and physical-state characterization
• Formulation development to achieve target sameness and performance
• In-house bioequivalence testing via IVRT and IVPT to support FDA submission

OTC Product Development

We develop over-the-counter topical products, including programs targeting common dermatological needs such as acne, wart, nail fungus, and eczema. We support both monograph and non-monograph pathways, adhering to the relevant standards while optimizing stability and consumer experience.

Cosmetic & Active Skin Care Formulation

Beyond drug products, we implement quality research into our cosmetic care products with functions in anti-aging, brightening, antioxidant, and barrier-support. With our in-house skin biomarker panel, we can verify the high performance of your formulations.

Contact us at jwu@neoventech.com.